File:Crypt branching high mag.jpg

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Summary

High magnification <a href="https://en.wikipedia.org/wiki/micrograph" class="extiw" title="w:micrograph">micrograph</a> of crypt branching in a case of <a href="https://en.wikipedia.org/wiki/Crohn%27s_disease" class="extiw" title="w:Crohn's disease">Crohn's disease</a> with active inflammation. <a href="https://en.wikipedia.org/wiki/H%26E_stain" class="extiw" title="w:H&E stain">H&E stain</a>. Colonic biopsy of the <a href="https://en.wikipedia.org/wiki/mucosa" class="extiw" title="w:mucosa">mucosa</a>.

The micrograph show numerous eosinophils. This suggest an infectious cause and/or inflammatory cause.

The findings in this image (alone) are not diagnostic for Crohn's disease.

Crypt branching is a sign of a chronic crypt destructive process. Causes of chronic crypt destruction that lead to crypt branching include:

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File history

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Date/TimeThumbnailDimensionsUserComment
current14:32, 9 January 2017Thumbnail for version as of 14:32, 9 January 20172,848 × 4,272 (3.72 MB)127.0.0.1 (talk)High magnification <a href="https://en.wikipedia.org/wiki/micrograph" class="extiw" title="w:micrograph">micrograph</a> of <b>crypt branching</b> in a case of <a href="https://en.wikipedia.org/wiki/Crohn%27s_disease" class="extiw" title="w:Crohn's disease">Crohn's disease</a> with active inflammation. <a href="https://en.wikipedia.org/wiki/H%26E_stain" class="extiw" title="w:H&E stain">H&E stain</a>. Colonic biopsy of the <a href="https://en.wikipedia.org/wiki/mucosa" class="extiw" title="w:mucosa">mucosa</a>. <p>The micrograph show numerous eosinophils. This suggest an infectious cause and/or inflammatory cause. </p> <p>The findings in this image (alone) are not diagnostic for Crohn's disease. </p> <p>Crypt branching is a sign of a chronic crypt destructive process. Causes of chronic crypt destruction that lead to crypt branching include: </p> <ul> <li> <a href="https://en.wikipedia.org/wiki/inflammatory_bowel_disease" class="extiw" title="w:inflammatory bowel disease">Inflammatory bowel disease</a> (e.g. ulcerative colitis, Crohn's disease), </li> <li> Persistent infectious colitides, and </li> <li> <a href="https://en.wikipedia.org/wiki/ischemic_colitis" class="extiw" title="w:ischemic colitis">Ischemic colitis</a>.</li> </ul> <h2><span class="mw-headline" id="Related_images">Related images</span></h2> <ul class="gallery mw-gallery-traditional"> <li class="gallerybox" style="width: 155px"><div style="width: 155px"> <div class="thumb" style="width: 150px;"><div style="margin:15px auto;"><a href="//commons.wikimedia.org/wiki/File:Cryptitis_high_mag.jpg" class="image"><img alt="" src="https://upload.wikimedia.org/wikipedia/commons/thumb/4/49/Cryptitis_high_mag.jpg/80px-Cryptitis_high_mag.jpg" width="80" height="120" srcset="https://upload.wikimedia.org/wikipedia/commons/thumb/4/49/Cryptitis_high_mag.jpg/120px-Cryptitis_high_mag.jpg 1.5x, https://upload.wikimedia.org/wikipedia/commons/thumb/4/49/Cryptitis_high_mag.jpg/160px-Cryptitis_high_mag.jpg 2x" data-file-width="2848" data-file-height="4272"></a></div></div> <div class="gallerytext"> <p>High mag. </p> </div> </div></li> <li class="gallerybox" style="width: 155px"><div style="width: 155px"> <div class="thumb" style="width: 150px;"><div style="margin:35px auto;"><a href="//commons.wikimedia.org/wiki/File:Cryptitis_intermed_mag.jpg" class="image"><img alt="" src="https://upload.wikimedia.org/wikipedia/commons/thumb/0/04/Cryptitis_intermed_mag.jpg/120px-Cryptitis_intermed_mag.jpg" width="120" height="80" srcset="https://upload.wikimedia.org/wikipedia/commons/thumb/0/04/Cryptitis_intermed_mag.jpg/180px-Cryptitis_intermed_mag.jpg 1.5x, https://upload.wikimedia.org/wikipedia/commons/thumb/0/04/Cryptitis_intermed_mag.jpg/240px-Cryptitis_intermed_mag.jpg 2x" data-file-width="4272" data-file-height="2848"></a></div></div> <div class="gallerytext"> <p>Intermed. mag. </p> </div> </div></li> </ul>
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