Placental site trophoblastic tumor
| Placental site trophoblastic tumor | |
|---|---|
| File:PSTT.jpg
Photomicrograph showing proliferating intermediate trophoblast with scares cytotophoblastic and systrophoblastic elements
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| Classification and external resources | |
| Specialty | Lua error in Module:Wikidata at line 446: attempt to index field 'wikibase' (a nil value). |
| ICD-O | 9104/1 |
| Patient UK | Placental site trophoblastic tumor |
| MeSH | D018245 |
Placental site trophoblastic tumor is a form of gestational trophoblastic disease, which is thought to arise from intermediate trophoblast.[1]
It may secrete human placental lactogen (human chorionic somatomammotropin),[2] and result in a false-positive pregnancy test.[3]
Placental Site Trophoblastic Tumor is a monophasic neoplasm of the implantation site intermediate trophoblast, and usually a benign lesion, which comprises less than 2% of all gestational trophoblastic proliferations. Preceding conditions include molar pregnancy(5%). Compared to choriocarcinoma or invasive mole, hemorrhage is less conspicuous and serum β-HCG level is low, making early diagnosis difficult.
Immunohistochemistry: Often stains with hPL, keratin, Mel-CAM, EGFR.
Prognosis : 10~20% of cases metastase leading to death.
Treatment : Because chemotherapy is ineffective; the patient should undergo hysterectomy.
References
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ http://library.med.utah.edu/WebPath/EXAM/MULTORG/fem1frm.html
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
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