ABCC13

ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene
Identifiers
Symbols	ABCC13 ; C21orf73; PRED6
External IDs	OMIM: 608835 GeneCards: ABCC13 Gene
Gene ontology Molecular function • ATP binding • ATPase activity, coupled to transmembrane movement of substances Cellular component • integral component of membrane Biological process • transmembrane transport Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	150000	n/a
Ensembl	ENSG00000243064	n/a
UniProt	Q9NSE7	n/a
RefSeq (mRNA)	NM_138726	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	Chr 21: 14.24 – 14.36 Mb	n/a
PubMed search	[1]	n/a

Putative ATP-binding cassette transporter sub-family C member 13 is a protein that in humans is encoded by the ABCC13 gene.

Function

This gene is a member of the superfamily of genes encoding ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This family member is part of the MRP subfamily, which is involved in multi-drug resistance, but the human locus is now thought to be a pseudogene incapable of encoding a functional ABC protein. Alternative splicing results in multiple transcript variants; however, not all variants have been fully described.

See also

• ATP-binding cassette transporter
• ABCC13 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.