Adhyperforin

Adhyperforin
	250px
Systematic (IUPAC) name
	(1R,5S,6R,7S)-4-Hydroxy-6-methyl-5-(2-methylbutanoyl)-1,3,7-tris(3-methyl-2-buten-1-yl)-6-(4-methyl-3-penten-1-yl)bicyclo[3.3.1]non-3-ene-2,9-dione
Clinical data
Legal status	Over-the-counter;
Routes of; administration	Oral
Identifiers
CAS Number	143183-63-5
ATC code	none
PubChem	CID: 9963735
ChemSpider	25066875
ChEMBL	CHEMBL388948
Chemical data
Formula	C36H54O4
Molecular mass	550.81156 g/mol
	SMILES CCC(C)C(=O)C12C(=C(C(=O)C(C1=O)(CC(C2(C)CCC=C(C)C)CC=C(C)C)CC=C(C)C)CC=C(C)C)O ;
	InChI InChI=1S/C36H54O4/c1-12-27(10)30(37)36-32(39)29(18-16-25(6)7)31(38)35(33(36)40,21-19-26(8)9)22-28(17-15-24(4)5)34(36,11)20-13-14-23(2)3/h14-16,19,27-28,39H,12-13,17-18,20-22H2,1-11H3/t27?,28-,34+,35+,36-/m0/s1 ; Key:DHPDSOCOUJHGHE-ACJQSPJVSA-N ;
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Adhyperforin is a phytochemical found in the members of the plant genus Hypericum including St. John's Wort.^[1] It has a very similar pharmacological profile to hyperforin and acts as a TRPC6 ion channel activator,^[1] thereby inhibiting the reuptake of various neurotransmitters including serotonin, norepinephrine, dopamine, GABA, and glutamate.^[1] Adhyperforin is found in St. John's Wort in levels approximately 1/10 those of hyperforin.^[1]

References

↑ ^1.0 ^1.1 ^1.2 ^1.3 Lua error in package.lua at line 80: module 'strict' not found.

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