Akuammicine

Akuammicine
Identifiers
CAS Number	639-43-0
ChemSpider	8489522
Jmol 3D model	Interactive image
PubChem	10314057
	InChI InChI=1S/C20H22N2O2/c1-3-12-11-22-9-8-20-14-6-4-5-7-15(14)21-18(20)17(19(23)24-2)13(12)10-16(20)22/h3-7,13,16,21H,8-11H2,1-2H3/b12-3-/t13-,16-,20+/m0/s1 Key: YZOMNXCYSIYMOX-UHFFFAOYSA-N ;
	SMILES C123C(=C(C4CC1N(CC3)CC4=CC)C(OC)=O)Nc1c2cccc1 ;
Properties
Chemical formula	C20H22N2O2
Molar mass	322.40
Appearance	white solid
Melting point	182 °C (360 °F; 455 K)
Vapor pressure	{{{value}}}
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

Akuammicine is an alkaloid found in Vinca minor and Aspidosperma. It is a μ-opioid receptor agonists which is also agonizes (but to a much lower, clinically insignificant degree) the κ and δ-opioid receptors. Agonistic activity at both human variants of the σ-sigma receptors has been indicated but is not yet proven, so have possible mechanisms of action at the NMDA receptor (antagonist) and glycine receptor.

Notes

Cite error: Invalid <references> tag; parameter "group" is allowed only.

Use <references />, or <references group="..." />

This biology article is a stub. You can help Wikipedia by expanding it.