BHF-177

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BHF-177
BHF-177 structure.png
Systematic (IUPAC) name
N-[(1R,2R,4S)-bicyclo[2.2.1]hept-2-yl]-2-methyl-5-[4-(trifluoromethyl)phenyl]-4-pyrimidinamine
Identifiers
CAS Number 917896-43-6 YesY
IUPHAR/BPS 5503
ChemSpider 26286940 YesY
Chemical data
Formula C19H20F3N3
Molecular mass 347.377 g/mol
  • C4CC2CC4CC2Nc1nc(C)ncc1-c3ccc(C(F)(F)F)cc3
  • InChI=1S/C19H20F3N3/c1-11-23-10-16(13-4-6-15(7-5-13)19(20,21)22)18(24-11)25-17-9-12-2-3-14(17)8-12/h4-7,10,12,14,17H,2-3,8-9H2,1H3,(H,23,24,25)/t12-,14+,17+/m0/s1 YesY
  • Key:ADHZHPOKTRHZGT-DXCKQFNASA-N YesY
  (verify)

BHF-177 is a compound used in scientific research which acts as a positive allosteric modulator at the GABAB receptor.[1] It was shown to reduce self-administration of nicotine in animal studies.[2]

References

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