Fusafungine
Clinical data | |
---|---|
AHFS/Drugs.com | International Drug Names |
Identifiers | |
CAS Number | 1393-87-9 ![]() |
ATC code | R02AB03 (WHO) |
DrugBank | DB08965 ![]() |
UNII | 65DD690W0C ![]() |
KEGG | D08002 ![]() |
Synonyms | Fusafungin |
Chemical data | |
Formula | C29H51N2O8 |
Molecular mass | 555.72 g/mol[1] |
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Fusafungine (INN), also known as fusafungin, is an active agent used in antibiotics for treatment of nasal and throat infection. It also possesses anti-inflammatory properties. Fusafungine is a mixture of enniatin cyclohexadepsipeptides made up of alternating D-α-hydroxyvaleric acid and L-N-methylamino acid residues,[2] produced by the ascomycete Fusarium lateritium, and marketed by Servier under the trade names Locabiotal, Bioparox, and Locabiosol.
According to a pooled analysis study done in the UK for the efficacy of fusafungine in rhinopharingitis, it was found that the proportion of patients who showed an improvement in symptoms from Day 0 to Day 4 of infection was 61.5% with fusafungine vs. 46.8% when compared to a placebo.[3]
References
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- ↑ Fusafungine at MeSH
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