Imeglimin

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Imeglimin
150px
Names
IUPAC name
(2S)-N6,N6,2-Trimethyl-1,2-dihydro-1,3,5-triazine-4,6-diamine
Identifiers
775351-65-0
ChemSpider 26232690
Jmol 3D model Interactive image
  • InChI=1S/C6H13N5/c1-4-8-5(7)10-6(9-4)11(2)3/h4H,1-3H3,(H3,7,8,9,10)/t4-/m1/s1
    Key: GFICWFZTBXUVIG-SCSAIBSYSA-N
  • InChI=1/C6H13N5/c1-4-8-5(7)10-6(9-4)11(2)3/h4H,1-3H3,(H3,7,8,9,10)/t4-/m1/s1
    Key: GFICWFZTBXUVIG-SCSAIBSYBC
  • C[C@H]1NC(=NC(=N1)N)N(C)C
Properties
C6H13N5
Molar mass 155.21 g·mol−1
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Imeglimin is an experimental drug being developed as an oral anti-diabetic. It is an oxidative phosphorylation blocker that acts to inhibit hepatic gluconeogenesis, increase muscle glucose uptake, and restore normal insulin secretion. It will be the first of a new class of anti-diabetic if it is approved.

Imeglimin is in development (completed phase IIb clinical trials) for use both as monotherapy and in combination with other type-2 diabetes treatments.[1][2]

Various research protocols are being known through various scientists. Early studies showed that imeglimin is as effective as metformin in regulating glycaemic control.[3]

References

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  2. http://www.reuters.com/article/2013/03/07/idUSnHUGGg5Jta+1e4+ONE20130307
  3. http://www.omicsonline.org/2155-6156/2155-6156-2-126.php#1


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