Leukocyte receptor tyrosine kinase
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Leukocyte receptor tyrosine kinase is an enzyme that in humans is encoded by the LTK gene.[1][2]
Function
The protein encoded by this gene is a member of the ALK/LTK receptor family of receptor tyrosine kinases (RTKs) whose ligand is unknown.[3] Closely related to the insulin receptor family of RTKs. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.[2]
Interactions
LTK has been shown to interact with IRS-1, Shc, and PIK3R1.[4][5]
References
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Further reading
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