List of U.S. Routes in Mississippi

Standard route shields
Highway names
Interstates:	Interstate X (I-X)
US Routes:	U.S. Route X (US X)
State:	Mississippi Highway X (MS X)
System links
Numbered Highways in Mississippi Interstate US State Unsigned

In the U.S. state of Mississippi, U.S. Routes are maintained by the Mississippi Department of Transportation (MDOT).

List of U.S. Routes

	U.S. Route 11 East New Orleans, Louisiana, to Rouses Point, New York Crosses the Louisiana state line near Nicholson; crosses the Alabama state line near Kewanee
	U.S. Route 45 Mobile, Alabama, to Ontonagon, Michigan Crosses the Alabama state line near State Line; crosses the Tennessee state line near Wenesoga
	U.S. Route 49 Gulfport, Mississippi, to Piggott, Arkansas Crosses the Arkansas state line near Lula; splits into US 49E and US 49W between Yazoo City and Tutwiler
	U.S. Route 51 La Place, Louisiana, to Hurley, Wisconsin Crosses the Louisiana state line near Osyka; crosses the Tennessee state line near Horn Lake
	U.S. Route 61 New Orleans, Louisiana, to Wyoming, Minnesota Crosses the Louisiana state line near Woodville; crosses the Tennessee state line near Lake View
	U.S. Route 72 Memphis, Tennessee, to Chattanooga, Tennessee Crosses the Tennessee state line near Barton; crosses the Alabama state line near Oldham
	U.S. Route 78 Memphis, Tennessee, to Charleston, South Carolina Crosses the Tennessee state line near Olive Branch; crosses the Alabama state line near Tremont
	U.S. Route 80 Dallas, Texas, to Tybee Island, Georgia Crosses the Louisiana state line near Vicksburg; crosses the Alabama state line near Kewanee
	U.S. Route 82 Alamogordo, New Mexico, to Brunswick, Georgia Crosses the Arkansas state line near Refuge; crosses the Alabama state line near New Hope
	U.S. Route 84 Pagosa Springs, Colorado, to Midway, Georgia Crosses the Louisiana state line near Natchez; crosses the Alabama state line near Waynesboro
	U.S. Route 90 Van Horn, Texas, to Jacksonville Beach, Florida Crosses the Louisiana state line near Pearlington; crosses the Alabama state line near Pecan
	U.S. Route 98 Washington, Mississippi, to Palm Beach, Florida Crosses the Alabama state line near Lucedale
	U.S. Route 278 Wickes, Arkansas, to Hilton Head Island, South Carolina Crosses the Arkansas state line near Refuge; crosses the Alabama state line near Gattman
	U.S. Route 425 Natchez, Mississippi, to Pine Bluff, Arkansas Crosses the Louisiana state line near Natchez

See also

• Mississippi portal
• U.S. Roads portal