Mycobacterium intracellulare
| Mycobacterium intracellulare | |
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M. intracellulare
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| Binomial name | |
| Mycobacterium intracellulare Runyon 1965,[1] ATCC 13950
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Mycobacterium intracellulare is a species of the phylum actinobacteria (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus Mycobacterium.
Description
"Gram-positive", nonmotile and acid-fast short to long rods.
Colony characteristics
- Usually smooth, rarely rough and nonpigmented colonies. Ageing colonies may become yellow.
Physiology
- Growth on Löwenstein-Jensen medium and Middlebrook 7H10 at 37°C after 7 or more days.
- Resistant to isoniazid, ethambutol, rifampin and streptomycin.
Differential characteristics
- M. intracellulare and Mycobacterium avium form the M. avium complex (MAC).
- Remarkable ITS heterogeneity within different M. intracellulare isolates.
Pathogenesis
- Most frequently encountered in pulmonary secretions from patients suffering from tuberculosis-like disease and from surgical specimens from such patients.
- When isolated from human secretions, it is often the etiologic agent of pulmonary disease, although frequently isolated as apparent casual resident
- Biosafety level 2
Type strain
Strain ATCC 13950 = CCUG 28005 = CIP 104243 = DSM 43223 = JCM 6384 = NCTC 13025.
References
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- ↑ Runyon, E. 1965. Pathogenic mycobacteria. Advances in Tuberculosis Research, 14, 235-287.
