Oleoyl-(acyl-carrier-protein) hydrolase
| acyl-ACP thioesterase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.2.14 | ||||||||
| CAS number | Template:CAS | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, an oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14) is an enzyme that catalyzes the chemical reaction
- oleoyl-[acyl-carrier-protein] + H2O
[acyl-carrier-protein] + oleate
Thus, the two substrates of this enzyme are [[oleoyl-[acyl-carrier-protein]]] and H2O, whereas its two products are acyl-carrier-protein and oleate.
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is oleoyl-[acyl-carrier-protein] hydrolase. Other names in common use include acyl-[acyl-carrier-protein] hydrolase, acyl-ACP-hydrolase, acyl-acyl carrier protein hydrolase, oleoyl-ACP thioesterase, and oleoyl-acyl carrier protein thioesterase. This enzyme participates in fatty acid biosynthesis.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2OWN and 2PFF.
References
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