PAXIP1

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). PAX-interacting protein 1 is a protein that in humans is encoded by the PAXIP1 gene.[1][2]

Function

This gene is a member of the paired box (PAX) gene family and encodes a nuclear protein with six BRCT (breast cancer carboxy-terminal) domains. This protein plays a critical role in maintaining genome stability, condensation of chromatin and progression through mitosis.[2]

Interactions

PAXIP1 has been shown to interact with PAX2[3] and TP53BP1.[4][5]

References

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Further reading

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