Papilloma
| Papilloma | |
|---|---|
| File:H&E 10x papilloma.jpg
Intraductal papilloma of breast, H&E, 10x
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| Classification and external resources | |
| Specialty | Lua error in Module:Wikidata at line 247: invalid escape sequence near '"^'. |
| ICD-O | 8050/0 |
| Patient UK | Papilloma |
| MeSH | D010212 |
A papilloma (plural papillomas or papillomata) (papillo- + -oma) is a benign epithelial tumor[1] growing exophytically (outwardly projecting) in nipple-like and often finger-like fronds. In this context papilla refers to the projection created by the tumor, not a tumor on an already existing papilla (such as the nipple).
When used without context, it frequently refers to infections (squamous cell papilloma) caused by human papillomavirus (HPV), such as warts. Human papillomavirus infection is a major cause of cervical cancer, although most HPV infections do not cause cancer. There are, however, a number of other conditions that cause papilloma, as well as many cases in which there is no known cause.
Contents
Description
A benign papillomatous tumor derived from epithelium. Cauliflower-like projections that arise from the mucosal surface. It may appear white or normal colored. It may be pedunculated or sessile. The average size is between 1–5 cm. No strong sex preference. The most common site was the palate-uvula area followed by tongue and lips. The durations ranged from weeks to 10 years.
Etiology
Immunoperoxidase stains have identified antigens of the human papillomavirus (HPV) types 6 and 11 in approximately 50% of cases of squamous cell papilloma.
Prognosis
There is no evidence that papillomas are premalignant.
Differential diagnosis
- Intraoral verruca vulgaris,
- Condyloma acuminatum, and
- Focal epithelial hyperplasia.
Note: differentiation is done accurately by microscopic examination only.
Treatment
Conservative surgical excision, recurrence is rare.
See also
- Inverted papilloma
- Squamous cell papilloma
- Urothelial papilloma
- Intraductal papilloma of breast
- Wart
- Papillomavirus
References
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Look up papilloma in Wiktionary, the free dictionary. |
- Choroid Plexus Papilloma - Palmer, Cheryl Ann and Daniel Keith Harrison; EMedicine; Jun 5, 2008
- Types of papilloma
- Squamous cell papilloma
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