Sibrotuzumab

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Sibrotuzumab
Monoclonal antibody
Type Whole antibody
Source Humanized (from mouse)
Target FAP
Identifiers
CAS Number 216669-97-5 N
ATC code none
 NYesY (what is this?)  (verify)

Sibrotuzumab is a humanized monoclonal antibody intended for the treatment of cancer. It binds to FAP[1][2]

In 2003 it failed a phase II clinical trial for metastatic colorectal cancer.[3]

References

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  3. Stromal antigen targeting by a humanised monoclonal antibody: an early phase II trial of sibrotuzumab in patients with metastatic colorectal cancer.


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