Template:PBB/116

Adenylate cyclase activating polypeptide 1 (pituitary)
PDB rendering based on 2d2p.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1GEA, 2D2P, 2JOD
Identifiers
Symbols	ADCYAP1 ; PACAP
External IDs	OMIM: 102980 MGI: 105094 HomoloGene: 869 ChEMBL: 5692 GeneCards: ADCYAP1 Gene
Gene ontology Molecular function • receptor signaling protein activity • receptor binding • neuropeptide hormone activity • protein binding • pituitary adenylate cyclase activating polypeptide activity • peptide hormone receptor binding Cellular component • extracellular region • intracellular Biological process • transmembrane receptor protein tyrosine kinase signaling pathway • activation of adenylate cyclase activity • neuropeptide signaling pathway • cell-cell signaling • female pregnancy • regulation of G-protein coupled receptor protein signaling pathway • positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway • cAMP-mediated signaling • neuron projection development • regulation of protein localization • positive regulation of GTPase activity • negative regulation of cell cycle • positive regulation of protein kinase activity • positive regulation of transcription from RNA polymerase II promoter • neurotrophin TRK receptor signaling pathway • positive regulation of ERK1 and ERK2 cascade • positive regulation of chemokine (C-C motif) ligand 5 production Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	116	11516
Ensembl	ENSG00000141433	ENSMUSG00000024256
UniProt	P18509	O70176
RefSeq (mRNA)	NM_001099733	NM_009625
RefSeq (protein)	NP_001093203	NP_033755
Location (UCSC)	Chr 18: 0.9 – 0.91 Mb	Chr 17: 93.2 – 93.21 Mb
PubMed search	[1]	[2]