XPO1

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Exportin 1 (XPO1), also known as chromosomal maintenance 1 (CRM1), is an eukaryotic protein that mediates the nuclear export of proteins, rRNA, snRNA, and some mRNA.[1][2][3][4]

Function

Exportin 1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.[5]

Interactions

XPO1 has been shown to interact with:

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See also

References

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Further reading

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External links


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