Ipsapirone

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Ipsapirone
File:Ipsapirone.svg
Systematic (IUPAC) name
9,9-dioxo-8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-
6-thia-8-azabicyclo[4.3.0]nona-1,3,5-trien-7-one
Clinical data
Legal status
  • Uncontrolled
Routes of
administration
Oral
Pharmacokinetic data
Biological half-life 1.3-2.7 hours
Identifiers
CAS Number 95847-70-4 YesY
ATC code none
PubChem CID: 56971
IUPHAR/BPS 42
ChemSpider 51365 YesY
UNII 6J9B11MN0K YesY
ChEMBL CHEMBL8412 YesY
Chemical data
Formula C19H23N5O3S
Molecular mass 401.484 g/mol
  • O=C2c1ccccc1S(=O)(=O)N2CCCCN4CCN(c3ncccn3)CC4
  • InChI=1S/C19H23N5O3S/c25-18-16-6-1-2-7-17(16)28(26,27)24(18)11-4-3-10-22-12-14-23(15-13-22)19-20-8-5-9-21-19/h1-2,5-9H,3-4,10-15H2 YesY
  • Key:TZJUVVIWVWFLCD-UHFFFAOYSA-N YesY
  (verify)

Ipsapirone is a selective 5-HT1A receptor partial agonist of the piperazine and azapirone chemical classes.[1] It has antidepressant and anxiolytic effects.[1] Ipsapirone was studied in several placebo-controlled trials for depression and continues to be used in research.[2]

See also

References

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