R7 (drug)
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Oral |
R7 is a prodrug of 7,8-dihydroxyflavone (7,8-DHF) with significantly improved potency and pharmacokinetics (namely oral bioavailability) that is currently in preclinical development for the treatment of Alzheimer's disease.[1] As a prodrug of 7,8-DHF, R7 is a selective agonist of TrkB, the main receptor of brain-derived neurotrophic factor (BDNF).[1] 7,8-DHF shows robust efficacy in a variety of animal models of Alzheimer's disease as well as other conditions, making R7 a highly promising potential therapeutic agent.[1] The chemical structure of the compound has yet to be published.[1]
See also
References
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