ALG2
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Alpha-1,3-mannosyltransferase ALG2 is an enzyme that is encoded by the ALG2 gene.[1] Mutations in the human gene are associated with congenital defects in glycosylation [2][3]
This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii).[3]
Interactions
ALG2 has been shown to interact with ANXA7[4] and ANXA11.[4]
References
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<references />, or <references group="..." />Further reading
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- Lua error in package.lua at line 80: module 'strict' not found. NB ALG-2 is NOT the protein product of the ALG2 gene.
- Lua error in package.lua at line 80: module 'strict' not found. NB ALG-2 is NOT the protein product of the ALG2 gene.
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- Lua error in package.lua at line 80: module 'strict' not found. NB ALG-2 is NOT the protein product of the ALG2 gene.
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- Lua error in package.lua at line 80: module 'strict' not found.
- Lua error in package.lua at line 80: module 'strict' not found. NB ALG-2 is NOT the protein product of the ALG2 gene.
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- Lua error in package.lua at line 80: module 'strict' not found. NB ALG-2 is NOT the protein product of the ALG2 gene.
External links
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