FUT4
From Infogalactic: the planetary knowledge core
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) | |
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Identifiers | |
Symbol | FUT4 |
Alt. symbols | CD15, FCT3A, ELFT, SSEA-1, LeX |
Entrez | 2526 |
HUGO | 4015 |
OMIM | 104230 |
RefSeq | NM_002033 |
UniProt | P22083 |
Other data | |
EC number | 2.4.1.152 |
Locus | Chr. 11 q21 |
Fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific), also known as FUT4, is an enzyme which in humans is encoded by the FUT4 gene.[1][2][3]
Function
The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).[4][5]
References
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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