FUT4

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fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
Identifiers
Symbol FUT4
Alt. symbols CD15, FCT3A, ELFT, SSEA-1, LeX
Entrez 2526
HUGO 4015
OMIM 104230
RefSeq NM_002033
UniProt P22083
Other data
EC number 2.4.1.152
Locus Chr. 11 q21

Fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific), also known as FUT4, is an enzyme which in humans is encoded by the FUT4 gene.[1][2][3]

Function

The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).[4][5]

References

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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