Clometerone

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Clometerone
Clometerone.svg
Systematic (IUPAC) name
6α-Chloro-16α-methylpregn-4-ene-3,20-dione
Identifiers
CAS Number 5591-27-5
ATC code none
PubChem CID: 14515731
ChemSpider 16736897
Synonyms 6α-chloro-16α-methylprogesterone
Chemical data
Formula C22H31ClO2
Molecular mass 362.933 g/mol
  • C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)CC[C@@]4([C@H]3CC[C@@]2([C@H]1C(=O)C)C)C)Cl
  • InChI=1S/C22H31ClO2/c1-12-9-17-15-11-19(23)18-10-14(25)5-7-21(18,3)16(15)6-8-22(17,4)20(12)13(2)24/h10,12,15-17,19-20H,5-9,11H2,1-4H3/t12-,15-,16+,17+,19+,20-,21-,22+/m1/s1
  • Key:UMRURYMAPMZKQO-NDKKBYRMSA-N

Clometerone (INN) (developmental code name L-38000), or clometherone (USAN), also known as 6α-chloro-16α-methylprogesterone, is a synthetic steroid and derivative of progesterone described as an antiandrogen and antiestrogen that was never marketed.[1][2] Based on structure-activity relationships, clometerone is likely a progestin, antigonadotropin, and antiandrogen, similarly to the related drugs chlormadinone acetate and cyproterone acetate.

References

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  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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