Gavilimomab

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Gavilimomab
Monoclonal antibody
Type Whole antibody
Source Mouse
Target CD147
Identifiers
CAS Number 244096-20-6 N
ATC code none
 NYesY (what is this?)  (verify)

Gavilimomab (also known as ABX-CBL) is a mouse monoclonal antibody intended for use as an immunosuppressive biologic treatment of glucocorticoid-resistant graft versus host disease. It binds to the antigen CD147.[1] Gavilimomab proved slightly less effective than standard antithymocyte globulin therapy.[2]

It was originally developed by Abgenix,[1] which was later acquired by Amgen.

References


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