HCN1
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 is a protein that in humans is encoded by the HCN1 gene.[1][2][3][4]
Contents
Function
Hyperpolarization-activated cation channels of the HCN gene family, such as HCN1, contribute to spontaneous rhythmic activity in both heart and brain.[4]
Tissue distribution
HCN1 channel expression is found in the sinoatrial node,[5][6] the neocortex, hippocampus, cerebellar cortex, dorsal root ganglion, trigeminal ganglion and brainstem.[7][8][9][10][11]
Interactions
HCN1 has been shown to interact with HCN2.[12][13]
Epilepsy
De novo mutations in HCN1 cause epilepsy .[14]
See also
References
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External links
- HCN1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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