KCNK7

Potassium channel, two pore domain subfamily K, member 7
Identifiers
Symbols	KCNK7 ; K2p7.1; TWIK3
External IDs	OMIM: 603940 MGI: 1341841 HomoloGene: 43131 IUPHAR: 519 GeneCards: KCNK7 Gene
Gene ontology Molecular function • voltage-gated ion channel activity • potassium channel activity • potassium ion leak channel activity Cellular component • plasma membrane • integral component of plasma membrane Biological process • potassium ion transport • synaptic transmission • stabilization of membrane potential • regulation of ion transmembrane transport • potassium ion transmembrane transport Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10089	16530
Ensembl	ENSG00000173338	ENSMUSG00000024936
UniProt	Q9Y2U2	Q9Z2T1
RefSeq (mRNA)	NM_005714	NM_001004138
RefSeq (protein)	NP_005705	NP_034739
Location (UCSC)	Chr 11: 65.59 – 65.6 Mb	Chr 19: 5.7 – 5.71 Mb
PubMed search	[1]	[2]

Potassium channel, subfamily K, member 7, also known as KCNK7 or K_2P7.1 is a protein which in humans is encoded by the KCNK7 gene. K_2P7.1 is a potassium channel containing two pore-forming P domains. Multiple transcript variants encoding different isoforms have been found for this gene.

Function

This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel; It may require other non-pore-forming proteins for activity.

See also

• Tandem pore domain potassium channel

External links

• KCNK7 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
• KCNK7 human gene location in the UCSC Genome Browser.
• KCNK7 human gene details in the UCSC Genome Browser.