EA-3834

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EA-3834
EA-3834 structure.png
Systematic (IUPAC) name
(1-methylpiperidin-4-yl) 2-hydroxy-3-methyl-2-phenylbutanoate
Identifiers
PubChem CID: 21150216
ChemSpider 20085385
Chemical data
Formula C17H25NO3
Molecular mass 291.384 g/mol
  • C1CN(C)CCC1OC(=O)C(O)(C(C)C)c2ccccc2
  • InChI=1S/C17H25NO3/c1-13(2)17(20,14-7-5-4-6-8-14)16(19)21-15-9-11-18(3)12-10-15/h4-8,13,15,20H,9-12H2,1-3H3
  • Key:IFXNWEDGILPSBA-UHFFFAOYSA-N
  (verify)

EA-3834 is a potent anticholinergic deliriant drug with a fairly long duration of action, related to the chemical warfare agent 3-Quinuclidinyl benzilate (QNB). It was developed under contract to Edgewood Arsenal during the 1960s as part of the US military chemical weapons program, during research to improve upon the properties of earlier agents such as QNB.

EA-3834 has a potency and central to peripheral effects ratio only slightly less than that of related compounds such as EA-3443, and is faster acting and shorter lasting, although not as much as other compounds such as 302196.[1][2]

See also

References

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  1. ↑ Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents, Volume 1 (1982). Commission on Life Sciences. The National Academies Press. pp200-204.
  2. ↑ Ketchum JS. Chemical Warfare Secrets Almost Forgotton. A Personal Story of Medical Testing of Army Volunteers with Incapacitating Chemical Agents During the Cold War. ChemBooks Inc 2006. ISBN 978-1-4243-0080-8
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