ADB-CHMINACA

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ADB-CHMINACA
ADB-CHMINACA.svg
Systematic (IUPAC) name
N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide
Clinical data
Legal status
Identifiers
CAS Number 1185887-13-1 YesY
PubChem CID: 77565944
ChemSpider 32741710
UNII 5BNC061EBB YesY
Chemical data
Formula C21H30N4O2
Molecular mass 370.24 g/mol
  • CC(C)(C)C(NC(=O)c2nn(CC1CCCCC1)c3ccccc23)C(N)=O
  • InChI=1S/C21H30N4O2/c1-21(2,3)18(19(22)26)23-20(27)17-15-11-7-8-12-16(15)25(24-17)13-14-9-5-4-6-10-14/h7-8,11-12,14,18H,4-6,9-10,13H2,1-3H3,(H2,22,26)(H,23,27)
  • Key:ZWCCSIUBHCZKOY-UHFFFAOYSA-N

ADB-CHMINACA (also known as MAB-CHMINACA) is an indazole-based synthetic cannabinoid. It is a potent agonist of the CB1 receptor with a binding affinity of Ki = 0.289 nM and was originally developed by Pfizer in 2009 as an analgesic medication.[1][2] It was identified in cannabinoid blends in Japan in early 2015.[3]

Side Effects

There have been a number of reported cases of deaths and hospitalizations in relation to this synthetic cannabinoid.[4][5][6][7][8][9][10][11]

Legal status

As of October 29, 2014 Louisiana placed ADB-CHMINACA into Schedule I by emergency scheduling.[12]

Sweden's public health agency suggested to classify ADB-CHMINACA as hazardous substance on November 10, 2014.[13]

ADB-CHMINACA is listed in the Fifth Schedule of the Misuse of Drugs Act (MDA) and therefore illegal in Singapore as of May 2015.[14]

The DEA announced its intent to place ADB-CHMINACA into Schedule I of the USA Controlled Substances Act on September 16, 2015.[15]

ADB-CHMINACA is illegal in Switzerland as of December 2015.[16]

See also

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References

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