Methylpentynol

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Methylpentynol
Meparfynol.svg
Systematic (IUPAC) name
3-methylpent-1-yn-3-ol
Clinical data
Trade names Oblivon
Identifiers
CAS Number 77-75-8 YesY
ATC code N05CM15 (WHO)
PubChem CID: 6494
ChemSpider 21106516 N
UNII B017BC5B1N YesY
Chemical data
Formula C6H10O
Molecular mass 98.143 g/mol
  • CCC(C)(C#C)O
  • InChI=1S/C6H10O/c1-4-6(3,7)5-2/h1,7H,5H2,2-3H3 N
  • Key:QXLPXWSKPNOQLE-UHFFFAOYSA-N N
 NYesY (what is this?)  (verify)

Methylpentynol (Methylparafynol, Dormison, Atemorin) is a tertiary hexanol with hypnotic/sedative and anticonvulsant effects. It was discovered by Bayer in 1913[1] and was used shortly thereafter for the treatment of insomnia, but its use was quickly phased out in response to newer drugs with far more favorable safety profiles.[2][3][4][5]

Synthesis

Methylpentynol is prepared by reaction of butanone with sodium acetylide.

See also

References

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  1. ↑ DE patent 289800, "Verfahren zur Darstellung der Oxyalkylderivate von Kohlenwasserstoffen", issued 1913-11-30, assigned to Bayer, Leverkusen 
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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  6. ↑ W. Grimene and H. Emde, German Patent 959,485 (1957).
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