SEMA7A
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) (SEMA7A) also known as CD108 (Cluster of Differentiation 108), is a human gene.[1]
SEMA7A is a membrane-bound semaphorin that associates with cell surfaces via a glycosylphosphatidylinositol (GPI) linkage. SEMA7A is also known as the John-Milton-Hagen (JMH) blood group antigen, an 80-kD glycoprotein expressed on activated lymphocytes and erythrocytes.[supplied by OMIM][1]
Contents
Genetics
This protein is known to have eight variants in the extracellular region: seven lie within the Sema domain and one within the PSI domain.
Molecular biology
This protein forms dimers.
Notes
This protein acts as a receptor for the malaria parasite Plasmodium falciparum.
See also
References
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Further reading
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External links
- SEMA7A protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
- John Milton Hagen blood group system in the BGMUT blood group antigen gene mutation database
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.