TRIB3

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Tribbles homolog 3 is a protein that in humans is encoded by the TRIB3 gene.[1][2][3]

Function

The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB, and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1.[3]

Interactions

TRIB3 has been shown to interact with:

References

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Further reading

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Stub icon

This article on a gene on human chromosome 20 is a stub. You can help Wikipedia by expanding it.
  1. ↑ 1.0 1.1 Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ 3.0 3.1 Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ 4.0 4.1 4.2 4.3 Lua error in package.lua at line 80: module 'strict' not found.
  5. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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