ITGA5
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Integrin alpha-5 is a protein that in humans is encoded by the ITGA5 gene.[1]
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.[2]
Interactions
ITGA5 has been shown to interact with GIPC1.[3]
See also
References
Further reading
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External links
- CD49e Antigen at the US National Library of Medicine Medical Subject Headings (MeSH)
- ITGA5 Info with links in the Cell Migration Gateway
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