ICI-204,448

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ICI-204,448
ICI-204448 structure.png
Systematic (IUPAC) name
2-(3-[1-([2-(3,4-dichlorophenyl)acetyl]-methylamino)-2-pyrrolidin-1-ylethyl]phenoxy)acetic acid
Identifiers
CAS Number 121264-04-8 YesY
PubChem CID: 3683
IUPHAR/BPS 1650
ChEMBL CHEMBL23472 N
Chemical data
Formula C23H26Cl2N2O4
Molecular mass 465.368 g/mol
  • C2CCCN2CC(c(ccc3)cc3OCC(O)=O)N(C)C(=O)Cc(cc1Cl)ccc1Cl
 NYesY (what is this?)  (verify)

ICI-204,448 is a drug which acts as a potent and peripherally selective κ-opioid agonist, with possible uses in the treatment of heart attack as well as anti-itching effects.[1][2] It is used in research to distinguish centrally from peripherally mediated kappa opioid receptor effects.[3][4]

References

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