Thiorphan

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Systematic (IUPAC) name
(±)-2-[(2-benzyl-3-sulfanyl-propanoyl)amino]acetic acid
Identifiers
CAS Number 76721-89-6 N
PubChem CID: 3132
DrugBank DB08626 N
ChemSpider 3020 YesY
UNII B79L7B5X3Z YesY
ChEMBL CHEMBL10247 YesY
Chemical data
Formula C12H15NO3S
Molecular mass 253.32 g/mol
  • C1=CC=C(C=C1)CC(CS)C(=O)NCC(=O)O
  • InChI=1S/C12H15NO3S/c14-11(15)7-13-12(16)10(8-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,13,16)(H,14,15) YesY
  • Key:LJJKNPQAGWVLDQ-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

Thiorphan is the active metabolite of the antidiarrheal racecadotril (acetorphan).[1] It prevents the degradation of endogenous enkephalins by acting as an enkephalinase inhibitor.[1]

See also

References

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