Prostaglandin EP1 receptor
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Prostaglandin E1 receptor 1 (EP1) is a 42kDa prostaglandin receptor. PTGER1 is its human gene.[1]
The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, Gq proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.[1]
See also
- Prostaglandin E2 receptor 2 (EP2)
- Prostaglandin E2 receptor 3 (EP3)
- Prostaglandin E2 receptor 4 (EP4)
- Eicosanoid receptor
References
External links
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Further reading
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
